IntelliPlexTM TORCH Plus
The TORCH complex is a set of perinatal infections that includes toxoplasmosis, rubella, cytomegalovirus, herpes simplex viruses 1 and 2, and others. These infections affect 1-5% of all live births and are teratogenic: they can cause miscarriage, stillbirth, neonatal death, or congenital diseases, depending on the stage of pregnancy at time of infection. Detection and diagnosis can be done through serologic testing and are crucial for effective implementation of appropriate treatments and therapies.
The IntelliPlex technology allows for the simultaneous testing of serum antibodies specific to antigens in the TORCH complex for both pregnant women and newborns. Each disc is coupled to a capture agent for IgG or IgM specific to one of the TORCH infections. By reacting the disc mix with serum sample, detection antibody, and streptavidin-phycoerythrin, thePlexBio 100 decodes each disc and measures its fluorescent signal in order to identify infections in the sample.
Presence of IgM antibodies indicates a current or recent infection, while the presence of IgG antibodies may be a sign of past infection or immunization. PlexBio provides both IgG and IgM assays for a more complete picture of infection history.
The IntelliPlexTM TORCH Plus IgG & IgM Kits include all reagents necessary to perform multiplex assays for the TORCH complex plus Chlamydia and Parvovirus.