IntelliPlex™ ALK Rearrangement Kit

The IntelliPlex™ ALK Rearrangement Kit is a qualitative molecular assay for the aberrant gene fusions detection on EML4-ALK, KIF5B-ALK, and TFG-ALK transcripts. The kit utilizes one-step RT-PCR and PlexBio's core πCode™ technology which enables 24 ALK variants to be identified in a single well using RNA samples extracted from formalin-fixed paraffin-embedded tissues (FFPET).

FEATURES

Detect 24 ALK fusion variants in one well test
Highly sensitive (5~1209 copies) to detect low levels of RNA variants
Only ≥50ng RNA sample required
Time to results in <6 hours for 96 samples per run (sample preparation included)

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Multi-targets Detection

Detectable 24 ALK fusion variants in one well

Low Sample Input

Only ≥50ng RNA sample extracted from FFPE tissues required

High Sensitivity

Detects low levels of RNA variants with a high sensitivity

Quick Turnaround Time

Sample to results in <6 hours with automated reporting

Overview

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Overview

The IntelliPlex™ ALK Rearrangement Kit is an in-vitro molecular test based on πCode™ technology and PlexBio's instrument platform to identify 24 fusion variants in ALK gene. πCode™ technology enables the multi-variants detection in single-well with RNA samples derived from formalin-fixed paraffin-embedded (FFPE) human tissues. The kit provides all necessary optimized reagents for the sensitive detection of low levels of RNA variants in a background of wild-type RNA by one-step RT-PCR and simultaneous PCR amplification of target cDNA. The testing results could deliver crucial molecular status to clinical evaluation.

Principle of πCode Multiplexing

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