Detectable 5 driver genes,
28 RNA variants in one well
Catalog Number:82033
IntelliPlex™ Lung Cancer Panel- FFPE RNA
The IntelliPlex™ Lung Cancer Panel comprises NSCLC driver genes' DNA mutations and RNA fusion variants detection for use with samples extracted from NSCLC formalin-fixed paraffin-embedded tissues (FFPET) or liquid biopsies such as plasma.
The FFPE RNA panel is a qualitative molecular assay for the detection of 28 RNA variant hotspots in ALK, ROS1, RET, NTRK1, and MET genes from FFPE samples in a single well by using PlexBio's core πCode technology.
FEATURES
The FFPE RNA panel is a qualitative molecular assay for the detection of 28 RNA variant hotspots in ALK, ROS1, RET, NTRK1, and MET genes from FFPE samples in a single well by using PlexBio's core πCode technology.
FEATURES
- Detect 5 driver genes, 28 RNA fusion variants in one well test
- Highly sensitive (10~89 copies) to detect low levels of RNA variants
- Only ≥50ng RNA sample required
- Time to results in <6 hours for 96 samples per run (sample preparation included)
Broad Target Coverage
Low Sample Input
Only ≥50ng RNA sample extracted from FFPE tissues required
High Sensitivity
Detects low levels of RNA variants with a high sensitivity
Quick Turnaround Time
Sample to results in <6 hours with automated reporting
Overview
The IntelliPlex™ Lung Cancer Panel- FFPE RNA is an in-vitro molecular test based on πCode™ technology and PlexBio's instrument platform to identify 28 RNA fusion variants in ALK, ROS1, RET, NTRK1, and MET genes in NSCLC. πCode™ technology enables the multi-variants detection in single-well with RNA samples derived from formalin-fixed paraffin-embedded (FFPE) human tissues. The kit provides all necessary optimized reagents for the sensitive detection of low levels of RNA variants in a background of wild-type genomic RNA by one-step RT-PCR and simultaneous PCR amplification of target cDNA. The genetic status evaluation from these NSCLC driver genes can impact the selection of and the response to targeted therapies.
Principle of πCode Multiplexing
OUR RESOURCES
IFU