Catalog Number:82025

IntelliPlex™ RET/NTRK1 Rearrangement Kit

The IntelliPlex RET/NTRK1 Rearrangement Kit is a qualitative molecular assay for the aberrant gene fusions detection on RET and NTRK1 genes. The kit utilizes one-step RT-PCR and PlexBio's core πCode technology which enables 14 RET and NTRK1 fusion variants to be identified in a single well using RNA samples extracted from formalin-fixed paraffin-embedded tissues (FFPET).

FEATURES
  • Detect 14 RET and NTRK1 fusion variants in one well test
  • Highly sensitive (12~486 copies) to detect low levels of RNA variants
  • Only ≥50ng RNA sample required
  • Time to results in <6 hours for 96 samples per run (sample preparation included)
multiplexing

Multi-targets Detection

Detectable 14 RET and NTRK1 fusion variants in one well
sample

Low Sample Input

Only ≥50ng RNA sample extracted from FFPE tissues required
high sensitivity

High Sensitivity

Detects low levels of RNA variants with a high sensitivity
quick turnaround time

Quick Turnaround Time

Sample to results in <6 hours with automated reporting 
Overview
The IntelliPlex RET/NTRK1 Rearrangement Kit is an in-vitro molecular test based on πCode technology and PlexBio's instrument platform to identify 14 fusion variants in RET and NTRK1 genes. πCode technology enables the multi-variants detection in single-well with RNA samples derived from formalin-fixed paraffin-embedded (FFPE) human tissues. The kit provides all necessary optimized reagents for the sensitive detection of low levels of RNA variants in a background of wild-type RNA by one-step RT-PCR and simultaneous PCR amplification of target cDNA. The testing results could deliver crucial molecular status to clinical evaluation.

Principle of πCode Multiplexing
OUR RESOURCES
IFU
Type
IFU
Publish Date
2022.02.16

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